expression profile data of human cancer cell lines Search Results


luciferase-expressing human gastric cancer cell line nugc-4-luc  (GenScript corporation)
90
GenScript corporation luciferase-expressing human gastric cancer cell line nugc-4-luc
Luciferase Expressing Human Gastric Cancer Cell Line Nugc 4 Luc, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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transcriptome data of human cancer cell lines (ccls)  (Broad Institute Inc)
90
Broad Institute Inc transcriptome data of human cancer cell lines (ccls)
Identification of the diverse patterns based on the PANoptosis gene list. (a) A total of 226 PANoptosis-related genes belonging to necroptosis, apoptosis, and pyroptosis were collected for downstream analysis. (b) The univariate Cox regression analysis and Spearman's sum rank test were performed in the HOVON cohort, which was set as the training cohort. 28 genes with prognostic prediction were screened out with p value <0.05. (c) An interaction network of prognostic PANoptosis-related genes. (d) The 618 patients in HOVON cohort were divided into three clusters, according to the consensus clustering analysis based on the <t>transcriptome</t> profile of PANoptosis-related genes. (e) The KM curves showing the differential overall survival among the three subgroups. (f) A heat map showing the expression of the prognostic PANoptosis related genes in different subgroups. The two-sided p value <0.05 was considered significant for all statistical analyses and shown as ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p < 0.0001.
Transcriptome Data Of Human Cancer Cell Lines (Ccls), supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rna-seq data of different human liver cancer cell lines  (Broad Institute Inc)
90
Broad Institute Inc rna-seq data of different human liver cancer cell lines
Identification of the diverse patterns based on the PANoptosis gene list. (a) A total of 226 PANoptosis-related genes belonging to necroptosis, apoptosis, and pyroptosis were collected for downstream analysis. (b) The univariate Cox regression analysis and Spearman's sum rank test were performed in the HOVON cohort, which was set as the training cohort. 28 genes with prognostic prediction were screened out with p value <0.05. (c) An interaction network of prognostic PANoptosis-related genes. (d) The 618 patients in HOVON cohort were divided into three clusters, according to the consensus clustering analysis based on the <t>transcriptome</t> profile of PANoptosis-related genes. (e) The KM curves showing the differential overall survival among the three subgroups. (f) A heat map showing the expression of the prognostic PANoptosis related genes in different subgroups. The two-sided p value <0.05 was considered significant for all statistical analyses and shown as ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p < 0.0001.
Rna Seq Data Of Different Human Liver Cancer Cell Lines, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rna expression data for 57 human breast cancer cell lines  (Broad Institute Inc)
90
Broad Institute Inc rna expression data for 57 human breast cancer cell lines
Identification of the diverse patterns based on the PANoptosis gene list. (a) A total of 226 PANoptosis-related genes belonging to necroptosis, apoptosis, and pyroptosis were collected for downstream analysis. (b) The univariate Cox regression analysis and Spearman's sum rank test were performed in the HOVON cohort, which was set as the training cohort. 28 genes with prognostic prediction were screened out with p value <0.05. (c) An interaction network of prognostic PANoptosis-related genes. (d) The 618 patients in HOVON cohort were divided into three clusters, according to the consensus clustering analysis based on the <t>transcriptome</t> profile of PANoptosis-related genes. (e) The KM curves showing the differential overall survival among the three subgroups. (f) A heat map showing the expression of the prognostic PANoptosis related genes in different subgroups. The two-sided p value <0.05 was considered significant for all statistical analyses and shown as ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p < 0.0001.
Rna Expression Data For 57 Human Breast Cancer Cell Lines, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human cancer cell line rna-seq data (tpm)  (Genentech inc)
90
Genentech inc human cancer cell line rna-seq data (tpm)
(A) Expression of PTF1A and other acinar regulators in normal human pancreas (n=2) and PDAC cell lines (n=41), derived from public <t>RNA-seq</t> datasets. Expression plotted in transcripts per million, with individual samples plotted in blue over violin plots representing all expressed genes in each sample. (B) Western blot of Ptf1a and tubulin (control) expression in Lenti-TET-Ptf1a derivatives of Panc1, MiaPaCa2, Su8686 and SW1990 cells, treated −/+ DOX (1 μg/ml) for 48 hrs. (C) Representative images from clonogenic growth assays of Panc1 and Su8686 Lenti-TET-Ptf1a cells, grown 2 weeks −/+ DOX and stained with crystal violet. (D) Quantification of relative clone numbers in indicated PDAC cell lines, transduced with Lenti-TET-EGFP (green) or Lenti-TET-Ptf1a (orange), grown 10–14 days −/+ DOX (open vs. closed circles). Distinct lowercase letters indicate p<0.05 from ANOVA followed by Tukey’s post-hoc test of DOX-treated Lenti-TET-Ptf1a cells. (E) Cumulative population doublings of indicated PDAC cells, transduced with EGFP or Ptf1a (green vs orange). Cells were counted and replated at constant densities every 3 days, and treated from day 1 onwards −/+ DOX (open vs. closed circles for individual experiments, dotted vs. solid lines representing means). * P<0.05, DOX-treated Ptf1a vs EGFP cells. (F) Expression of indicated genes in PDAC cell lines transduced with Lenti-TET-Ptf1a, grown 48 hrs −/+ DOX (blue vs. orange), and analyzed by RT-qPCR (ΔΔCt method, normalized to PPIA expression within each sample and untreated Panc1 cells across samples).
Human Cancer Cell Line Rna Seq Data (Tpm), supplied by Genentech inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human cancer cell line rna-seq data (tpm)/product/Genentech inc
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human breast carcinoma cells not expressing nuclear estrogen receptors cancer cell line  (Informa UK Limited)
90
Informa UK Limited human breast carcinoma cells not expressing nuclear estrogen receptors cancer cell line
(A) Expression of PTF1A and other acinar regulators in normal human pancreas (n=2) and PDAC cell lines (n=41), derived from public <t>RNA-seq</t> datasets. Expression plotted in transcripts per million, with individual samples plotted in blue over violin plots representing all expressed genes in each sample. (B) Western blot of Ptf1a and tubulin (control) expression in Lenti-TET-Ptf1a derivatives of Panc1, MiaPaCa2, Su8686 and SW1990 cells, treated −/+ DOX (1 μg/ml) for 48 hrs. (C) Representative images from clonogenic growth assays of Panc1 and Su8686 Lenti-TET-Ptf1a cells, grown 2 weeks −/+ DOX and stained with crystal violet. (D) Quantification of relative clone numbers in indicated PDAC cell lines, transduced with Lenti-TET-EGFP (green) or Lenti-TET-Ptf1a (orange), grown 10–14 days −/+ DOX (open vs. closed circles). Distinct lowercase letters indicate p<0.05 from ANOVA followed by Tukey’s post-hoc test of DOX-treated Lenti-TET-Ptf1a cells. (E) Cumulative population doublings of indicated PDAC cells, transduced with EGFP or Ptf1a (green vs orange). Cells were counted and replated at constant densities every 3 days, and treated from day 1 onwards −/+ DOX (open vs. closed circles for individual experiments, dotted vs. solid lines representing means). * P<0.05, DOX-treated Ptf1a vs EGFP cells. (F) Expression of indicated genes in PDAC cell lines transduced with Lenti-TET-Ptf1a, grown 48 hrs −/+ DOX (blue vs. orange), and analyzed by RT-qPCR (ΔΔCt method, normalized to PPIA expression within each sample and untreated Panc1 cells across samples).
Human Breast Carcinoma Cells Not Expressing Nuclear Estrogen Receptors Cancer Cell Line, supplied by Informa UK Limited, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rfp-expressing hela human cervical cancer cell-line cells  (GenTarget)
90
GenTarget rfp-expressing hela human cervical cancer cell-line cells
(A) Expression of PTF1A and other acinar regulators in normal human pancreas (n=2) and PDAC cell lines (n=41), derived from public <t>RNA-seq</t> datasets. Expression plotted in transcripts per million, with individual samples plotted in blue over violin plots representing all expressed genes in each sample. (B) Western blot of Ptf1a and tubulin (control) expression in Lenti-TET-Ptf1a derivatives of Panc1, MiaPaCa2, Su8686 and SW1990 cells, treated −/+ DOX (1 μg/ml) for 48 hrs. (C) Representative images from clonogenic growth assays of Panc1 and Su8686 Lenti-TET-Ptf1a cells, grown 2 weeks −/+ DOX and stained with crystal violet. (D) Quantification of relative clone numbers in indicated PDAC cell lines, transduced with Lenti-TET-EGFP (green) or Lenti-TET-Ptf1a (orange), grown 10–14 days −/+ DOX (open vs. closed circles). Distinct lowercase letters indicate p<0.05 from ANOVA followed by Tukey’s post-hoc test of DOX-treated Lenti-TET-Ptf1a cells. (E) Cumulative population doublings of indicated PDAC cells, transduced with EGFP or Ptf1a (green vs orange). Cells were counted and replated at constant densities every 3 days, and treated from day 1 onwards −/+ DOX (open vs. closed circles for individual experiments, dotted vs. solid lines representing means). * P<0.05, DOX-treated Ptf1a vs EGFP cells. (F) Expression of indicated genes in PDAC cell lines transduced with Lenti-TET-Ptf1a, grown 48 hrs −/+ DOX (blue vs. orange), and analyzed by RT-qPCR (ΔΔCt method, normalized to PPIA expression within each sample and untreated Panc1 cells across samples).
Rfp Expressing Hela Human Cervical Cancer Cell Line Cells, supplied by GenTarget, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rfp-expressing hela human cervical cancer cell-line cells - by Bioz Stars, 2026-05
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rna-sequencing data of 675 commonly used human cancer cell lines  (Genentech inc)
90
Genentech inc rna-sequencing data of 675 commonly used human cancer cell lines
(A) Expression of PTF1A and other acinar regulators in normal human pancreas (n=2) and PDAC cell lines (n=41), derived from public <t>RNA-seq</t> datasets. Expression plotted in transcripts per million, with individual samples plotted in blue over violin plots representing all expressed genes in each sample. (B) Western blot of Ptf1a and tubulin (control) expression in Lenti-TET-Ptf1a derivatives of Panc1, MiaPaCa2, Su8686 and SW1990 cells, treated −/+ DOX (1 μg/ml) for 48 hrs. (C) Representative images from clonogenic growth assays of Panc1 and Su8686 Lenti-TET-Ptf1a cells, grown 2 weeks −/+ DOX and stained with crystal violet. (D) Quantification of relative clone numbers in indicated PDAC cell lines, transduced with Lenti-TET-EGFP (green) or Lenti-TET-Ptf1a (orange), grown 10–14 days −/+ DOX (open vs. closed circles). Distinct lowercase letters indicate p<0.05 from ANOVA followed by Tukey’s post-hoc test of DOX-treated Lenti-TET-Ptf1a cells. (E) Cumulative population doublings of indicated PDAC cells, transduced with EGFP or Ptf1a (green vs orange). Cells were counted and replated at constant densities every 3 days, and treated from day 1 onwards −/+ DOX (open vs. closed circles for individual experiments, dotted vs. solid lines representing means). * P<0.05, DOX-treated Ptf1a vs EGFP cells. (F) Expression of indicated genes in PDAC cell lines transduced with Lenti-TET-Ptf1a, grown 48 hrs −/+ DOX (blue vs. orange), and analyzed by RT-qPCR (ΔΔCt method, normalized to PPIA expression within each sample and untreated Panc1 cells across samples).
Rna Sequencing Data Of 675 Commonly Used Human Cancer Cell Lines, supplied by Genentech inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rna-sequencing data of 675 commonly used human cancer cell lines - by Bioz Stars, 2026-05
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gene expression data of the human h1 cell line  (Epigenomics ag)
90
Epigenomics ag gene expression data of the human h1 cell line
(A) Expression of PTF1A and other acinar regulators in normal human pancreas (n=2) and PDAC cell lines (n=41), derived from public <t>RNA-seq</t> datasets. Expression plotted in transcripts per million, with individual samples plotted in blue over violin plots representing all expressed genes in each sample. (B) Western blot of Ptf1a and tubulin (control) expression in Lenti-TET-Ptf1a derivatives of Panc1, MiaPaCa2, Su8686 and SW1990 cells, treated −/+ DOX (1 μg/ml) for 48 hrs. (C) Representative images from clonogenic growth assays of Panc1 and Su8686 Lenti-TET-Ptf1a cells, grown 2 weeks −/+ DOX and stained with crystal violet. (D) Quantification of relative clone numbers in indicated PDAC cell lines, transduced with Lenti-TET-EGFP (green) or Lenti-TET-Ptf1a (orange), grown 10–14 days −/+ DOX (open vs. closed circles). Distinct lowercase letters indicate p<0.05 from ANOVA followed by Tukey’s post-hoc test of DOX-treated Lenti-TET-Ptf1a cells. (E) Cumulative population doublings of indicated PDAC cells, transduced with EGFP or Ptf1a (green vs orange). Cells were counted and replated at constant densities every 3 days, and treated from day 1 onwards −/+ DOX (open vs. closed circles for individual experiments, dotted vs. solid lines representing means). * P<0.05, DOX-treated Ptf1a vs EGFP cells. (F) Expression of indicated genes in PDAC cell lines transduced with Lenti-TET-Ptf1a, grown 48 hrs −/+ DOX (blue vs. orange), and analyzed by RT-qPCR (ΔΔCt method, normalized to PPIA expression within each sample and untreated Panc1 cells across samples).
Gene Expression Data Of The Human H1 Cell Line, supplied by Epigenomics ag, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Identification of the diverse patterns based on the PANoptosis gene list. (a) A total of 226 PANoptosis-related genes belonging to necroptosis, apoptosis, and pyroptosis were collected for downstream analysis. (b) The univariate Cox regression analysis and Spearman's sum rank test were performed in the HOVON cohort, which was set as the training cohort. 28 genes with prognostic prediction were screened out with p value <0.05. (c) An interaction network of prognostic PANoptosis-related genes. (d) The 618 patients in HOVON cohort were divided into three clusters, according to the consensus clustering analysis based on the transcriptome profile of PANoptosis-related genes. (e) The KM curves showing the differential overall survival among the three subgroups. (f) A heat map showing the expression of the prognostic PANoptosis related genes in different subgroups. The two-sided p value <0.05 was considered significant for all statistical analyses and shown as ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p < 0.0001.

Journal: International Journal of Clinical Practice

Article Title: Machine Learning-Based Integrated Analysis of PANoptosis Patterns in Acute Myeloid Leukemia Reveals a Signature Predicting Survival and Immunotherapy

doi: 10.1155/2024/5113990

Figure Lengend Snippet: Identification of the diverse patterns based on the PANoptosis gene list. (a) A total of 226 PANoptosis-related genes belonging to necroptosis, apoptosis, and pyroptosis were collected for downstream analysis. (b) The univariate Cox regression analysis and Spearman's sum rank test were performed in the HOVON cohort, which was set as the training cohort. 28 genes with prognostic prediction were screened out with p value <0.05. (c) An interaction network of prognostic PANoptosis-related genes. (d) The 618 patients in HOVON cohort were divided into three clusters, according to the consensus clustering analysis based on the transcriptome profile of PANoptosis-related genes. (e) The KM curves showing the differential overall survival among the three subgroups. (f) A heat map showing the expression of the prognostic PANoptosis related genes in different subgroups. The two-sided p value <0.05 was considered significant for all statistical analyses and shown as ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, and ∗∗∗∗ p < 0.0001.

Article Snippet: Transcriptome data of human cancer cell lines (CCLs) were downloaded from the Broad Institute-Cancer Cell Line Encyclopedia project (CCLE, https://sites.broadinstitute.org/ccle/ ) and the CERES scores, the score to evaluate the dependency of the certain gene in the CCL, which indicated that the score was negative correlation with the possible significance of the gene in cell proliferation of the certain CCL, were downloaded from the dependency map portal (DepMap, https://depmap.org/portal/ ).

Techniques: Expressing

(A) Expression of PTF1A and other acinar regulators in normal human pancreas (n=2) and PDAC cell lines (n=41), derived from public RNA-seq datasets. Expression plotted in transcripts per million, with individual samples plotted in blue over violin plots representing all expressed genes in each sample. (B) Western blot of Ptf1a and tubulin (control) expression in Lenti-TET-Ptf1a derivatives of Panc1, MiaPaCa2, Su8686 and SW1990 cells, treated −/+ DOX (1 μg/ml) for 48 hrs. (C) Representative images from clonogenic growth assays of Panc1 and Su8686 Lenti-TET-Ptf1a cells, grown 2 weeks −/+ DOX and stained with crystal violet. (D) Quantification of relative clone numbers in indicated PDAC cell lines, transduced with Lenti-TET-EGFP (green) or Lenti-TET-Ptf1a (orange), grown 10–14 days −/+ DOX (open vs. closed circles). Distinct lowercase letters indicate p<0.05 from ANOVA followed by Tukey’s post-hoc test of DOX-treated Lenti-TET-Ptf1a cells. (E) Cumulative population doublings of indicated PDAC cells, transduced with EGFP or Ptf1a (green vs orange). Cells were counted and replated at constant densities every 3 days, and treated from day 1 onwards −/+ DOX (open vs. closed circles for individual experiments, dotted vs. solid lines representing means). * P<0.05, DOX-treated Ptf1a vs EGFP cells. (F) Expression of indicated genes in PDAC cell lines transduced with Lenti-TET-Ptf1a, grown 48 hrs −/+ DOX (blue vs. orange), and analyzed by RT-qPCR (ΔΔCt method, normalized to PPIA expression within each sample and untreated Panc1 cells across samples).

Journal: Developmental cell

Article Title: Prevention and reversion of pancreatic tumorigenesis through a differentiation-based mechanism

doi: 10.1016/j.devcel.2019.07.012

Figure Lengend Snippet: (A) Expression of PTF1A and other acinar regulators in normal human pancreas (n=2) and PDAC cell lines (n=41), derived from public RNA-seq datasets. Expression plotted in transcripts per million, with individual samples plotted in blue over violin plots representing all expressed genes in each sample. (B) Western blot of Ptf1a and tubulin (control) expression in Lenti-TET-Ptf1a derivatives of Panc1, MiaPaCa2, Su8686 and SW1990 cells, treated −/+ DOX (1 μg/ml) for 48 hrs. (C) Representative images from clonogenic growth assays of Panc1 and Su8686 Lenti-TET-Ptf1a cells, grown 2 weeks −/+ DOX and stained with crystal violet. (D) Quantification of relative clone numbers in indicated PDAC cell lines, transduced with Lenti-TET-EGFP (green) or Lenti-TET-Ptf1a (orange), grown 10–14 days −/+ DOX (open vs. closed circles). Distinct lowercase letters indicate p<0.05 from ANOVA followed by Tukey’s post-hoc test of DOX-treated Lenti-TET-Ptf1a cells. (E) Cumulative population doublings of indicated PDAC cells, transduced with EGFP or Ptf1a (green vs orange). Cells were counted and replated at constant densities every 3 days, and treated from day 1 onwards −/+ DOX (open vs. closed circles for individual experiments, dotted vs. solid lines representing means). * P<0.05, DOX-treated Ptf1a vs EGFP cells. (F) Expression of indicated genes in PDAC cell lines transduced with Lenti-TET-Ptf1a, grown 48 hrs −/+ DOX (blue vs. orange), and analyzed by RT-qPCR (ΔΔCt method, normalized to PPIA expression within each sample and untreated Panc1 cells across samples).

Article Snippet: Human cancer cell line RNA-seq data (TPM), Genentech , EMBL-EBI Expression Atlas , https://www.ebi.ac.uk/gxa/experiments/E-MTAB-2706/Downloads?ref=aebrowse.

Techniques: Expressing, Derivative Assay, RNA Sequencing, Western Blot, Control, Staining, Transduction, Quantitative RT-PCR

KEY RESOURCE TABLE

Journal: Developmental cell

Article Title: Prevention and reversion of pancreatic tumorigenesis through a differentiation-based mechanism

doi: 10.1016/j.devcel.2019.07.012

Figure Lengend Snippet: KEY RESOURCE TABLE

Article Snippet: Human cancer cell line RNA-seq data (TPM), Genentech , EMBL-EBI Expression Atlas , https://www.ebi.ac.uk/gxa/experiments/E-MTAB-2706/Downloads?ref=aebrowse.

Techniques: Recombinant, Electron Microscopy, Expressing, Plasmid Preparation